is_manufactured_by has function has role has component immunizes against disease immunizes recipient immunizes against pathogen has drug brand name hepatitis B Hepatitis B virus Homo sapiens FDA licensed vaccine role USA licensed human vaccine preventive vaccine function prophylactic vaccine recombinant vector vaccine vaccine adjuvant recombinant vector vaccine role Hepatitis B virus vaccine Hepatitis B surface antigen vaccine HEPLISAV-B vaccine 125428 For prevention of infection caused by all known subtypes of hepatitis B virus. HEPLISAV-B is approved for use in adults 18 years of age and older HBsAg-1018 Oliver He Kallan Roan https://www.ncbi.nlm.nih.gov/pubmed/22342916 A Hepatitis B surface antigen viral vaccine that utilizes a cytidine-phosphate-guanosine oligodeoxynucleotide (CpGODN) 1018, as an adjuvant. https://www.fda.gov/media/108745/download?attachment Randi Vita http://purl.bioontology.org/ontology/RXNORM/1994348 vaccine vaccine monovalent role licensed human hepatitis B virus vaccine Dynavax Technologies Corporation Heplisav-B