induces immune profile microbial derivative vaccine adjuvant Th1-biased immune profile rOv-ASP-1 vaccine adjuvant https://www.ncbi.nlm.nih.gov/pubmed/?term=24681229 43 Sara Lustigman Recombinant O. volvulus activation-associated secreted protein-1 A vaccine adjuvant that is a potent adjuvant for antibody and cellular responses to protein, polypeptide and small peptide antigens. rOv-ASP-1 stands for Recombinant Onchocerca volvulus activation-associated secreted protein-1. https://www.ncbi.nlm.nih.gov/pubmed/?term=26795365 https://www.ncbi.nlm.nih.gov/pubmed/?term=22615877 rOv-ASP-1 https://www.ncbi.nlm.nih.gov/pubmed/?term=18341617 Pubmed References: Chemical Nature: (1) Protein Mechanism of Action: unknown Immune profile induced: Th1 Other Features/Characteristics: (1) Induces CD8 T cells, (2) provides innate protection, (3) promotes antibody affinity maturation. By routes: IM Point of Contact: Sara Lustigman, New York Blood Center Wolfgang Leitner https://www.ncbi.nlm.nih.gov/pubmed/?term=1583768 VAC: https://vac.niaid.nih.gov/view?id=43 https://www.ncbi.nlm.nih.gov/pubmed/?term=32471056 Oliver He https://www.ncbi.nlm.nih.gov/pubmed/?term=29764680 vaccine adjuvant https://www.ncbi.nlm.nih.gov/pubmed/?term=18675867 https://www.ncbi.nlm.nih.gov/pubmed/?term=25736195 https://violinet.org/vaxjo/vaxjo_detail.php?c_vaxjo_id=189