has function has role has component immunizes against disease immunizes recipient immunizes against pathogen blocks transmission of pathogen via vaccine vaccine immunity response transferrable to organism malaria Plasmodium falciparum Anopheles <genus> Homo sapiens Plasmodium falciparum gametocyte Plasmodium falciparum vaccine preventive vaccine function prophylactic vaccine subunit vaccine subunit vaccine role PFS25/28 in Matrix M vaccine PFS25/28 in Matrix M vaccine transmission-blocking vaccine Plasmodium falciparum Pfs25