induces immune profile target receptor C-type lectin domain family 4 member E liposome-based vaccine adjuvant Th1/Th17 mixed immune profile CAF01 vaccine adjuvant Ari Joffe https://clinicaltrials.gov/ct2/show/NCT01141205 https://www.ncbi.nlm.nih.gov/pubmed/?term=21124731 https://clinicaltrials.gov/ct2/show/NCT03926728 A vaccine adjuvant is a gadoteridol-loaded cationic adjuvant formulation 01 that induced a Th1/Th17 type of immune response. Chemical Nature: Liposome system Mechanism of Action: n/a Immune profile induced: Th1/Th17 Route of immunization: IP, IM, IN, SQ, ID, SC, SL, intratracheal, endotracheal, Fish vaccination Point of Contact: Gabriel Kristian Pedersen, Staten Serum Institute (SSI) Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=31539263 https://www.ncbi.nlm.nih.gov/pubmed/?term=30555488 https://www.ncbi.nlm.nih.gov/pubmed/?term=29699790 https://www.ncbi.nlm.nih.gov/pubmed/?term=34044110 https://www.ncbi.nlm.nih.gov/pubmed/?term=26394776 https://www.ncbi.nlm.nih.gov/pubmed/?term=18776936 https://www.ncbi.nlm.nih.gov/pubmed/?term=30291987 https://www.ncbi.nlm.nih.gov/pubmed/?term=21124731 https://www.ncbi.nlm.nih.gov/pubmed/?term=29358939 https://www.ncbi.nlm.nih.gov/pubmed/?term=33072125 https://www.ncbi.nlm.nih.gov/pubmed/?term=35585969 https://www.ncbi.nlm.nih.gov/pubmed/?term=26494626 https://www.ncbi.nlm.nih.gov/pubmed/?term=26379666 https://www.ncbi.nlm.nih.gov/pubmed/?term=35124896 https://www.ncbi.nlm.nih.gov/pubmed/?term=34358167 https://www.ncbi.nlm.nih.gov/pubmed/?term=29541075 https://www.ncbi.nlm.nih.gov/pubmed/?term=31130946 https://www.ncbi.nlm.nih.gov/pubmed/?term=31906072 https://www.ncbi.nlm.nih.gov/pubmed/?term=32106599 https://www.ncbi.nlm.nih.gov/pubmed/?term=19492047 https://www.ncbi.nlm.nih.gov/pubmed/?term=33422991 https://www.ncbi.nlm.nih.gov/pubmed/?term=28414746 https://www.ncbi.nlm.nih.gov/pubmed/?term=33066267 https://www.ncbi.nlm.nih.gov/pubmed/?term=27958370 https://www.ncbi.nlm.nih.gov/pubmed/?term=23308247 https://www.ncbi.nlm.nih.gov/pubmed/?term=30984200 https://www.ncbi.nlm.nih.gov/pubmed/?term=20505822 https://www.ncbi.nlm.nih.gov/pubmed/?term=27525651 https://www.ncbi.nlm.nih.gov/pubmed/?term=23873630 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT00922363 https://clinicaltrials.gov/ct2/show/NCT01009762 https://clinicaltrials.gov/ct2/show/NCT02787109 https://clinicaltrials.gov/ct2/show/NCT01141205 https://clinicaltrials.gov/ct2/show/NCT03926728 https://www.ncbi.nlm.nih.gov/pubmed/?term=30555488 CAF-01 Gabriel Kristian Pedersen https://violinet.org/vaxjo/vaxjo_detail.php?c_vaxjo_id=151 Oliver He vaccine adjuvant https://www.ncbi.nlm.nih.gov/pubmed/?term=29699790 75 https://clinicaltrials.gov/ct2/show/NCT02787109 https://www.ncbi.nlm.nih.gov/pubmed/?term=18776936 Wolfgang Leitner VAC: https://vac.niaid.nih.gov/view?id=75 https://clinicaltrials.gov/ct2/show/NCT01009762 https://www.ncbi.nlm.nih.gov/pubmed/?term=30291987 CAF01 https://www.ncbi.nlm.nih.gov/pubmed/?term=26394776 https://www.ncbi.nlm.nih.gov/pubmed/?term=34044110 https://www.ncbi.nlm.nih.gov/pubmed/?term=31539263 https://www.ncbi.nlm.nih.gov/pubmed/?term=29358939 https://clinicaltrials.gov/ct2/show/NCT00922363