induces immune profile target receptor protein MB21D1 microbial derivative vaccine adjuvant Th1/Th2/Th17 mixed immune profile CDG vaccine adjuvant PMID:24307739 A vaccine adjuvant that is the bacterial second messenger (3'-5')-cyclic-di-guanosine-monophosphate (c-di-GMP). Yuping Zheng CDG vaccine adjuvant https://violinet.org/vaxjo/vaxjo_detail.php?c_vaxjo_id=210