induces immune profile target receptor Toll-like receptor 9 Th1-biased immune profile TLR9 agonist vaccine adjuvant NADA vaccine adjuvant vaccine adjuvant https://violinet.org/vaxjo/vaxjo_detail.php?c_vaxjo_id=478 Hasin Rehana Josh Monickaraj PMID:36868876 The slow-release synthetic oligodeoxynucleotide (ODN) adjuvant triggers an immune response by initially sensing through pattern recognition receptors (PRRs), such as TLRs, which leads to the activation of innate immune cells like dendritic cells. NADA oligonucleotide vaccine adjuvant