has function has role immunizes against disease immunizes recipient test in lab animal model breast cancer Mus musculus Homo sapiens recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role breast cancer vaccine Recombinant Vaccinia DF3/MUC1 Vaccine cancer vaccine Jie Zheng Gene name: KLK3 PMID:9101412 Jimmy Guo 4582 Virginia He NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2510 https://github.com/vaccineontology/VO/issues/338 Gene name: MUC1 A vaccinia virus based vaccine expressing human tumor associated epithelial mucin (DF3 antigen; MUC1). MUC1 antigen, a membrane bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in various tumors such as breast, prostate, and ovarian cancers. This vaccine could be used in development of immunotherapeutics against cancers expressing MUC1. 5281 NCT: https://clinicaltrials.gov/ct2/show/NCT00071942 Oliver He VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5281 354 therapeutic cancer vaccine