has function has role immunizes against disease immunizes recipient test in lab animal model cancer Mus musculus Homo sapiens therapeutic vaccine function peptide vaccine vaccine in clinical trial role peptide vaccine role synthetic peptides E-PRA and E-PSM vaccine NCT: https://clinicaltrials.gov/ct2/show/NCT00423254 5496 PMID:21760528 https://github.com/vaccineontology/VO/issues/412 Oliver He VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5496 cancer vaccine Virginia He Gene name: S100A6 Jie Zheng 6277 NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C67098 Jimmy Guo A cancer vaccine consisting of E-PRA and E-PSM, two synthetic peptide analogs of PRAME (PReferential Antigen MElanoma) and PSMA (Prostate Specific Membrane Antigen), with potential immunostimulating activity. Upon direct administration into lymph nodes, synthetic peptides E-PRA and E-PSM vaccine may sitmulate a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing tumor cells. PRAME and PSMA are tumor-associated antigens upregulated and expressed on the cell surfaces of certain tumor cell types. therapeutic cancer vaccine