has function has role immunizes against disease immunizes recipient cervical cancer Homo sapiens recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role cervical cancer vaccine Quadrivalent Human Papillomavirus (types 6, 11, 16, 18) Recombinant Vaccine NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61087 Jimmy Guo A non-infectious recombinant, quadrivalent vaccine prepared from the highly purified virus-like particles (VLPs) of the major capsid (L1) protein of human papillomavirus (HPV) Types 6, 11, 16, and 18 with immunoprophylactic activity. The immunoprohylactic efficacy of L1 VLP vaccines, such as recombinant human papillomavirus quadrivalent vaccine, appear to be mediated by the development of humoral immune responses. HPV Types 16 and 18 account for approximately 70% of cervical cancers and HPV Types 6 and 11 account for approximately 90% of genital warts. 25479185 NCT: https://clinicaltrials.gov/ct2/show/NCT00411749 5406 Gene name: L1 Virginia He VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5406 Oliver He Jie Zheng cancer vaccine PMID:35997582 therapeutic cancer vaccine