has function has role immunizes against disease immunizes recipient cervical cancer Homo sapiens recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role recombinant viral vector vaccine cervical cancer vaccine Recombinant Human Papillomavirus Nonavalent Vaccine cancer vaccine Jimmy Guo 25479185 Jie Zheng Gene name: L1 PMID:26772631 Gene name: TPBG Oliver He Virginia He NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C119664 7162 5342 A non-infectious, recombinant, nonavalent vaccine prepared from highly purified virus-like particles (VLPs) comprised of the major capsid (L1) proteins from human papillomavirus (HPV) types 6, 11, 16, 18, 31, 33, 45, 52, and 58, with active immunizing activity. Upon administration, the recombinant HPV nonavalent vaccine activates the immune system to produce antibodies against the 9 HPV types. This protects against HPV infection and HPV-related cancers. Altogether, HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 account for the majority of the HPV types that cause cervical, vulvar, vaginal and anal cancers.Ê VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5342 therapeutic cancer vaccine