has function has role immunizes against disease immunizes recipient cervical cancer Homo sapiens recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role cervical cancer vaccine Verpasep Caltespen Vaccine Gene name: HSPD1 Virginia He A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. Jimmy Guo VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5542 cancer vaccine NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2811 PMID:16691066 NCT: https://clinicaltrials.gov/ct2/show/NCT00493545 1489079 3329 5542 Gene name: E7 Oliver He Jie Zheng therapeutic cancer vaccine