has function has role immunizes against disease immunizes recipient test in lab animal model lung cancer Mus musculus Homo sapiens therapeutic vaccine function peptide vaccine vaccine in clinical trial role peptide vaccine role lung cancer vaccine PR-151 Peptide Vaccine Jie Zheng NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38121 5272 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5272 NCT: https://clinicaltrials.gov/ct2/show/NCT00049218 PMID:29301826 A tumor-specific peptide encoded by patient-specific mutant p53 oncogene with potential immunostimulatory properties. The peptide (LPTGQDL) contains a frame shift mutation at amino acid position 134. It was used to pulse dendritic cells, which are then used in the adoptive immunotherapy setting and may stimulate the host immune system to mount a specific cytotoxic T lymphocyte response against tumor cells expressing the p35 mutation. Oliver He https://github.com/vaccineontology/VO/issues/125 7157 Gene name: TP53 Jimmy Guo cancer vaccine Virginia He https://github.com/vaccineontology/VO/issues/193 therapeutic cancer vaccine