has function has role immunizes against disease immunizes recipient test in lab animal model melanoma Mus musculus Homo sapiens melanoma vaccine therapeutic vaccine function peptide vaccine vaccine in clinical trial role peptide vaccine role synthetic melanoma-associated antigens vaccine Oliver He A cancer vaccine containing synthetic epitope peptides derived from melanoma tumor-associated antigens (TAAs), including melanoma-melanocyte antigen gp100(280-288), melanoma-associated antigen tyrosinase(1-9), and melanoma-associated antigen melan-A(27-35). Upon administration, synthetic melanoma-associated antigens vaccine may stimulate a cytotoxic T-lymphocyte immune response against melanoma cells that express TAAs which share epitopes with the vaccine epitope peptides, resulting in tumor cell lysis. Gene name: PMEL - obsolete 6490 Jie Zheng https://github.com/vaccineontology/VO/issues/411 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5217 5217 NCT: https://clinicaltrials.gov/ct2/show/NCT00116597 cancer vaccine NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48639 Virginia He Jimmy Guo PMID:11874634 therapeutic cancer vaccine