has function has role immunizes against disease immunizes recipient melanoma Homo sapiens melanoma vaccine therapeutic vaccine function DNA vaccine role vaccine in clinical trial role Xenogeneic Tyrosinase DNA vaccine Virginia He 5416 7299 Jimmy Guo NCT: https://clinicaltrials.gov/ct2/show/NCT00471133 A plasmid DNA vaccine, encoding an epitope of mouse tyrosinase, with potential antineoplastic activity. Administered via intramuscular electroporation, vaccination with xenogeneic tyrosinase DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) immune responses against melanoma cells that express tyrosinase, resulting in decreased tumor growth. NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C68839 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5416 PMID:4019903 Jie Zheng Oliver He Gene name: Tyrosinase cancer vaccine therapeutic cancer vaccine DNA cancer vaccine