has function has role immunizes against disease immunizes recipient test in lab animal model ovarian cancer Mus musculus Homo sapiens therapeutic vaccine function peptide vaccine vaccine in clinical trial role peptide vaccine role ovarian cancer vaccine P53-Synthetic Long Peptides Vaccine https://github.com/vaccineontology/VO/issues/59 5278 cancer vaccine Virginia He Gene name: TP53 7157 Oliver He A peptide vaccine consisting of 10 synthetic long peptides (SLPs), 25-30 amino acids in size and derived from the middle portion of p53 (amino acids 70-251), mixed with the adjuvant Montanide ISA-51 with potential immunostimulatory and antitumor activities. Upon administration, p53 synthetic long peptide (70-251) vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against p53-expressing tumor cells. p53, a tumor associated antigen (TAA), may be overexpressed in variety of cancer cell types. Jimmy Guo PMID:26334096 NCT: https://clinicaltrials.gov/ct2/show/NCT00844506 NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C82420 Jie Zheng VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5278 therapeutic cancer vaccine