has function has role immunizes against disease immunizes recipient lung cancer Homo sapiens recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role lung cancer vaccine Autologous Dendritic Cell-Adenovirus CCL21 Vaccine Gene name: CCL21 Ibrahim Seleznev A cancer vaccine comprised of autologous dendritic cells (DCs) that have been transduced ex vivo with an adenoviral vector containing the CCL21 gene with potential immunostimulatory and antineoplastic activities. Upon intratumoral administration, autologous dendritic cell-adenovirus CCL21 vaccine expresses the chemokine CCL21, which may induce an antitumoral cytotoxic immune response in the tumor microenvironment. CCL21 [chemokine (C-C motif) ligand 21] has been shown to attract antigen presenting cells (APCs), like leukocytes and DCs, and natural killer (NK) cells and their T-cell effectors to induce a cytotoxic immune response. cancer vaccine NCT: https://clinicaltrials.gov/ct2/show/NCT03546361 6366 Eliyas Asfaw 5030 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5030 Jie Zheng https://github.com/vaccineontology/VO/issues/252 Oliver He therapeutic cancer vaccine