has function has role immunizes against disease immunizes recipient melanoma Homo sapiens melanoma vaccine recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role autologous melanoma Lysate/KLH-pulsed autologous dendritic cell vaccine Ibrahim Seleznev VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5213 https://github.com/vaccineontology/VO/issues/275 cancer vaccine A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous melanoma cells containing tumor associated antigens (TAAs) and conjugated to the immunostimulant Keyhole limpet hemocyanin (KLH), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate/KLH-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against melanoma cells, which may result in melanoma cell lysis. KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy. 3123 5213 Gene name: HLA-DRB1 Oliver He Jie Zheng Eliyas Asfaw therapeutic cancer vaccine