has function has role immunizes against disease immunizes recipient melanoma ovarian cancer Homo sapiens melanoma vaccine recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role ovarian cancer vaccine autologous tumor-associated peptide antigen-pulsed dendritic cell vaccine Gene name: SPANXB1 PMID:18528294 54763 53340 8852 Jie Zheng Oliver He VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5035 https://github.com/vaccineontology/VO/issues/289 728695 Gene name: SPA17 Gene name: ROPN1 Eliyas Asfaw A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with specific tumor-associated peptide antigens (TAPA), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous TAPA-pulsed DC vaccine exposes the immune system to the specific TAPAs, which may result in cytotoxic T-lymphocyte (CTL)-mediated immune responses against the TAPA-expressing cancer cells. This leads to cancer cell lysis. This vaccine is specific towards peptides derived from the following proteins: sperm autoantigenic protein 17 (SP17), ropporin, A-kinase anchor protein 4 (AKAP4), pituitary tumor-transforming 1 (PTTG1) and SPANX family member B (SPANX-B). Ibrahim Seleznev Gene name: AKAP4 9232 PMID:23482679 Gene name: PTTG1 5035 cancer vaccine therapeutic cancer vaccine