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     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
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     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000006"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001818"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/RO_0000085 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000085">
        <rdfs:label xml:lang="en">has function</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001011 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001011">
        <rdfs:label>immunizes against disease</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001243 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001243">
        <rdfs:label>immunizes recipient</rdfs:label>
    </ObjectProperty>
    


    <!-- 
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    <!-- http://purl.obolibrary.org/obo/DOID_1909 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_1909">
        <rdfs:label xml:lang="en">melanoma</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000422 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000422">
        <rdfs:label>melanoma vaccine</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000562 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000562">
        <rdfs:label>therapeutic vaccine function</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000631 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000631">
        <rdfs:label>vaccine in clinical trial role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007325 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0007325">
        <rdfs:label>allogeneic HLA-A2/4-1BB ligand-expressing melanoma vaccine</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007658"/>
        <rdfs:subClassOf>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        <rdfs:subClassOf>
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                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <ns3:IAO_0000115>A cancer vaccine that consists of an allogeneic cell line that has a high expression level of melanoma molecules (HLA A2/4-1BB Ligand), and has been genetically modified to induce a strong immune response. Stimulation of the immune response against the tumor can help destroy residual tumor in melanoma patients with very high risk for disease recurrence and in patients with relatively low tumor burden who already got first line treatment for their disease.</ns3:IAO_0000115>
        <ns3:IAO_0000117>Jie Zheng</ns3:IAO_0000117>
        <ns3:IAO_0000117>Hayleigh Kahn</ns3:IAO_0000117>
        <ns3:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01861938</ns3:IAO_0000119>
        <ns3:OGG_0000000006>8744</ns3:OGG_0000000006>
        <ns3:OGG_0000000006>3105</ns3:OGG_0000000006>
        <rdfs:comment>Gene name: HLA-A</rdfs:comment>
        <rdfs:comment>Gene name: 4-1BBL</rdfs:comment>
        <ns3:VO_0001818>6313</ns3:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <ns3:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6313</ns3:IAO_0000119>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007657 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0007657">
        <rdfs:label>therapeutic cancer vaccine</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007658 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0007658">
        <rdfs:label>whole cell cancer vaccine</rdfs:label>
    </Class>
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