has function has role immunizes against disease immunizes recipient brain cancer Homo sapiens recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role brain cancer vaccine CMV pp65 Peptide-pulsed Autologous Dendritic Cell Vaccine A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with the human cytomegalovirus (CMV) phosphoprotein pp65, with potential immunostimulatory and antineoplastic activities. Upon administration, the CMV pp65 peptide-pulsed autologous DC vaccine exposes the immune system to the CMV pp65 peptide, which may result in a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells leading to cell lysis. The CMV pp65 protein, also called the 65 kDa lower matrix phosphoprotein, is the primary component of the enveloped subviral particle of CMV and is expressed in certain tumor types, such as glioblastoma 4985 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4985 https://github.com/vaccineontology/VO/issues/385 Eliyas Asfaw cancer vaccine Gene name: UL83 https://academic.oup.com/neuro-oncology/article/22/Supplement_3/iii306/6018727 Jie Zheng Oliver He Ibrahim Seleznev 3077579 therapeutic cancer vaccine