has function has role immunizes against disease immunizes recipient liver cancer Homo sapiens therapeutic vaccine function vaccine in clinical trial role liver cancer vaccine Cytokine-Induced Killer Cells Vaccine VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5070 PMID:23210562 174 cancer vaccine https://github.com/vaccineontology/VO/issues/391 Gene name: AFP Oliver He A preparation of autologous lymphocytes with potential immunopotentiating and antineoplastic activities. Cytokine-induced killer (CIK) cells are CD3- and CD56-positive, non-major histocompatibility complex (MHC)-restricted, natural killer (NK)-like T lymphocytes, generated ex-vivo by incubation of peripheral blood lymphocytes (PBLs) with anti-CD3 monoclonal antibody, interleukin (IL)-2, IL-1, and interferon gamma (IFN-gamma) and then expanded. When reintroduced back to patients after autologous stem cell transplantation, CIK cells may recognize and kill tumor cells associated with minimal residual disease (MRD). CIK cells may have enhanced cytotoxic activity compared to lymphokine-activated killer (LAK) cells. Jie Zheng Ibrahim Seleznev 5070 Eliyas Asfaw therapeutic cancer vaccine