has function has role immunizes against disease immunizes recipient prostate cancer breast cancer ovarian cancer Homo sapiens conjugate vaccine therapeutic vaccine function conjugate vaccine role vaccine in clinical trial role prostate cancer vaccine breast cancer vaccine ovarian cancer vaccine MUC1-KLH conjugate vaccine Justin Song cancer vaccine 5251 Jie Zheng VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5251 https://github.com/vaccineontology/VO/issues/549 A peptide vaccine, containing human tumor-associated epithelial mucin (MUC1) conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with MUC1-KLH conjugate vaccine may stimulate humoral and cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing the MUC1 antigen. In this vaccine, MUC1 antigen is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in an aberrant or deglycosylated form in various cancers such as those of the breast, prostate, and ovary. Yuanyi (Penny) Pan Oliver He 4582 Gene name: MUC1 therapeutic cancer vaccine