has function has role immunizes against disease immunizes recipient leukemia Homo sapiens therapeutic vaccine function vaccine in clinical trial role leukemia cancer vaccine Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells Vaccine Justin Song VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5004 cancer vaccine Oliver He Jie Zheng https://github.com/vaccineontology/VO/issues/476 Yuanyi (Penny) Pan 5004 A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with corpses of apoptotic leukemic cells, with potential immunostimulatory and antineoplastic activities. Upon vaccination, autologous dendritic cells pulsed with leukemic apoptotic corpse may activate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte (CTL) response against leukemic cells expressing leukemia-associated antigens, which may result in leukemic cell lysis and inhibition of tumor cell growth. Apoptotic tumor cell corpses contain an array of tumor associated antigens therapeutic cancer vaccine