has function has role vaccinated in route immunizes against disease immunizes recipient brain cancer Homo sapiens therapeutic vaccine function vaccine in clinical trial role intradermal route brain cancer vaccine dendritic cell tumor peptide vaccine A cancer vaccine composed of dendritic cells pulsed with peptide epitopes that stimulate cytotoxic T lymphocyte anti-tumor activity. This vaccine is used to treat diffuse hemispheric glioma with a H3 G34 mutation that has come back (recurrent) and/or is growing, spreading, or getting worse (progressive). It is made with the patient's own white blood cells and peptide-pulsed dendritic cells, which may help the body build an effective immune response to kill tumor cells. It is combined with immunotherapy monoclonal antibodies, such as nivolumab and ipilimumab, which also may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Hayleigh Kahn cancer vaccine 6282 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6282 Jie Zheng NCT: https://clinicaltrials.gov/study/NCT05457959 NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C1987 therapeutic cancer vaccine whole cell cancer vaccine