has function has role immunizes against disease immunizes recipient lymphoma Homo sapiens conjugate vaccine therapeutic vaccine function conjugate vaccine role vaccine in clinical trial role lymphoma vaccine follicular lymphoma, patient-specific, soluble protein idiotype vaccine 6290 A cancer vaccine directed against the soluble protein idiotype of an individual follicular lymphoma with potential antineoplastic activity. The vaccine may induce an idiotype-specific cytotoxic T-lymphocyte (CTL) response against follicular lymphoma cells expressing the idiotype, resulting in tumor cell lysis. Idiotypic vaccinations have the capacity of inducing an idiotype- and tumor-specific immune response, inducing specific immune responses able to kill in vivo follicular lymphoma cells, and prolonging survival of responding patients. This vaccine may contribute to preventing relapse indefinitely in responding patients. Jie Zheng cancer vaccine VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6290 NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C71036 NCT: https://clinicaltrials.gov/study/NCT00530140 Hayleigh Kahn therapeutic cancer vaccine