has function has role immunizes against disease immunizes recipient cancer Homo sapiens therapeutic vaccine function vaccine in clinical trial role Folate-FITC vaccine 5317 Yuanyi (Penny) Pan Oliver He PMID:22855837 2348 A conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, circulating anti-fluorescein antibodies may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity. Gene name: FOLR1 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5317 Jie Zheng https://github.com/vaccineontology/VO/issues/128 cancer vaccine Justin Song therapeutic cancer vaccine