has function has role vaccinated in route immunizes against disease immunizes recipient breast cancer Homo sapiens therapeutic vaccine function peptide vaccine vaccine in clinical trial role peptide vaccine role intradermal route breast cancer vaccine therapeutic cancer vaccine HER2 ICD peptide vaccine 2064 A cancer vaccine made from peptides that may help the body build an effective immune response to kill tumor cells. Patients with HER2 positive locally advanced breast cancer can be vaccinated with a HER2 Intracellular Domain (ICD) peptide-based vaccine administered concurrently with trastuzumab. The vaccine may lead to an immune response (HER2 specific T cell immunity and/or the development of intramolecular epitope spreading). VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6352 cancer vaccine 6352 NCT: https://clinicaltrials.gov/study/NCT00343109 Gene name: HER-2/neu Jie Zheng Hayleigh Kahn