has function has role vaccinated in route immunizes against disease immunizes recipient melanoma Homo sapiens melanoma vaccine recombinant vector vaccine therapeutic vaccine function vaccine in clinical trial role recombinant vector vaccine role intradermal route therapeutic cancer vaccine hyperacute-melanoma vaccine cancer vaccine Hayleigh Kahn Gene name: Ggta1 NCT: https://clinicaltrials.gov/study/NCT00300612 14594 A cancer vaccine composed of irradiated allogeneic melanoma cell lines (HAM-1, HAM-2 and HAM-3). These cell lines have been transduced with a recombinant Moloney murine leukemia virus (MoMLV)-based retroviral vector expressing the murine alpha(1,3)GT gene, a mouse gene that causes the production of a foreign pattern of protein-sugars on the cell surface. The immune response to the foreign substance could stimulate the immune system to attack the patient's own cancer cells that have similar proteins without this sugar pattern, causing the tumor to remain stable or shrink. 6298 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6298 Jie Zheng