has function has role immunizes against disease immunizes recipient brain cancer Homo sapiens therapeutic vaccine function peptide vaccine vaccine in clinical trial role peptide vaccine role brain cancer vaccine therapeutic cancer vaccine P30-linked EphA2/CMV pp65/survivin peptide vaccine P30-EPS NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C187131 6362 A cancer vaccine comprised of three immunogenic tetanus toxoid epitope P30-linked tumor-associated antigen (TAA) peptides, P30-linked Ephrin receptor A2 (EphA2), P30-linked cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) and P30-linked survivin, with potential immunostimulating and antineoplastic activities. The vaccine may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing EphA2, CMV pp65 and survivin. Hiltonol is used as an adjuvant to stimulate or enhance the activation of your immune system. The vaccine and adjuvant may help treat HLA-A*0201 positive patients with a newly diagnosed, unmethylated, and untreated World Health Organization (WHO) grade IV malignant glioma. Gene name: survivin Jie Zheng Hayleigh Kahn 332 1969 VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6362 Gene name: EphA2 cancer vaccine NCT: https://clinicaltrials.gov/study/NCT05283109