has function has role immunizes against disease immunizes recipient cancer Homo sapiens therapeutic vaccine function vaccine in clinical trial role therapeutic cancer vaccine whole cell cancer vaccine transgenic lymphocyte immunization vaccine 7015 NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C38720 cancer vaccine PMID:12653092 6358 Jie Zheng VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6358 A cancer vaccine made as patient's lymphocytes are rendered transgenic for a gene coding for selected portion of telomerase an enzyme expressed in the vast majority of cancer cells. Transgenic cells are then returned to the patient to produce an immune response targeted at cancer cells expressing telomerase. The transgenic cells serve as antigen- presenting cells (APCs) with the dual function of antigen synthesis and presentation. Vaccination produces an immune response targeting cancer cells expressing telomerase. Hayleigh Kahn NCT: https://clinicaltrials.gov/study/NCT00061035 Gene name: telomerase