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    <!-- 
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001818"/>
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    <AnnotationProperty rdf:about="http://purl.org/dc/terms/date"/>
    


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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

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        <rdfs:label xml:lang="en">has role</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001011 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001011">
        <rdfs:label>immunizes against disease</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003355 -->

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        <rdfs:label>immunizes against pathogen</rdfs:label>
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        <rdfs:label>test in lab animal model</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/DOID_11077 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_11077">
        <rdfs:label xml:lang="en">brucellosis</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10090 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10090">
        <rdfs:label>Mus musculus</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/NCBITaxon_235 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_235">
        <rdfs:label>Brucella abortus</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000208 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000208">
        <rdfs:label>vaccine in research role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001134 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0001134">
        <rdfs:label>live attenuated Brucella abortus vaccine</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0009037 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0009037">
        <rdfs:label>live attenuated Brucella abortus strain 544 vaccine</rdfs:label>
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        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-10-25T08:06:33Z</dcterms:date>
        <ns3:IAO_0000115>Live attenuated Brucella abortus vaccine using live co2-dependent Brucella abortus 544 bacteria. Vaccinated mice showed accelerated decrease in bacterial counts preventing multiplication of challenge strain in spleens and livers compared to normal mice. Vaccination induced acquired resistance characterized by an accelerated decreasing phase of bacterial counts after challenge, with near elimination of bacteria in spleen and liver by day six post-challenge.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=11955</oboInOwl:hasDbXref>
        <ns3:IAO_0000117> Jie Zheng</ns3:IAO_0000117>
        <ns3:VO_0001818>11955</ns3:VO_0001818>
        <ns3:IAO_0000119>PMID:821385</ns3:IAO_0000119>
        <ns3:IAO_0000117>VaxAgent </ns3:IAO_0000117>
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        <rdfs:label>live attenuated vaccine role</rdfs:label>
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