has role immunizes against disease immunizes against pathogen test in lab animal model brucellosis Mus musculus Brucella abortus vaccine in research role live attenuated Brucella abortus vaccine live attenuated Brucella abortus delta norD delta znuA vaccine 2026-10-25T08:06:33Z VaxAgent Live attenuated Brucella abortus vaccine using live attenuated mutant strain with deletions in nord and znua genes and lacz marker. Znbaz was significantly more protective than the conventional RB51 vaccine by more than four orders of magnitude and was completely cleared from mouse spleens within eight weeks post-vaccination. Vaccination with znbaz elicited elevated numbers of ifn-γ+, tnf-α+, and polyfunctional ifn-γ+ tnf-α+ cd4+ and cd8+ T cells, indicating a diverse and potent T cell-mediated. VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=12284 Jie Zheng PMID:27639282 vaccine 12284 live attenuated vaccine role