has role immunizes against disease immunizes against pathogen salmonellosis brucellosis Brucella abortus Salmonella enterica subsp. enterica serovar Typhimurium combination vaccine role vaccine in research role recombinant vector vaccine role combination vaccine Salmonella vaccine Brucella abortus recombinant vector vaccine live attenuated Brucella abortus vaccine live attenuated Brucella abortus BLS PrpA Omp19 SodC Salmonella Typhimurium vector vaccine 2026-10-25T08:06:33Z 12321 Combination vaccine using live attenuated Brucella abortus BLS PrpA omp19 sodc salmonella typhimurium vector vaccine. Immunized goats showed significantly higher protection demonstrated by lower bacterial loads in most tissues, reduced expression of Brucella antigens in spleen, kidney, and lung, and ameliorated histopathological lesions compared to non-immunized controls. Significantly higher serum igg titers against individual Brucella antigens and elevated interferon-γ production from peripheral blood mononuclear cells in vaccinated groups compared to non-immunized goats. VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=12321 VaxAgent Jie Zheng PMID:29929362 vaccine live attenuated vaccine role