has role immunizes against disease immunizes against pathogen test in lab animal model brucellosis Mus musculus Brucella abortus vaccine in research role live attenuated Brucella abortus vaccine live attenuated Brucella abortus mutant A19mut2 vaccine 2026-10-25T08:06:33Z PMID:37515088 12456 vaccine Live attenuated Brucella abortus vaccine using live attenuated mutant strain with modified lipopolysaccharide due to gene replacement. A19mut2 showed decreased residual virulence compared to A19 but induced significant humoral and cellular. Induced significant humoral immunity (igg and subtypes) and cellular immunity (ifn-γ and IL10 cytokine release) in vaccinated mice. VaxAgent VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=12456 Jie Zheng live attenuated vaccine role