has role immunizes against disease immunizes against pathogen test in lab animal model brucellosis Mus musculus Brucella melitensis vaccine in research role live attenuated Brucella melitensis vaccine live attenuated Brucella melitensis plsC gene deletion vaccine 2026-10-25T08:06:33Z PMID:39186777 VaxAgent VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=12478 Live attenuated Brucella melitensis vaccine using deletion mutant of the plsc gene, which is involved in phospholipid biosynthesis. Plsc deletion mutant showed protective efficacy similar to the reference Brucella melitensis strain Rev. 1 vaccine but with shorter persistence in the spleen. Jie Zheng vaccine 12478 live attenuated vaccine role