has role immunizes against disease immunizes against pathogen test in lab animal model brucellosis Mus musculus Brucella abortus vaccine in research role live attenuated Brucella abortus vaccine live attenuated Brucella abortus strain A19 btpB deletion vaccine 2026-10-25T08:06:33Z Jie Zheng VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=12522 PMID:41694393 VaxAgent Live attenuated Brucella abortus vaccine using live attenuated Brucella abortus strain A19 with btpb gene deletion. Δbtpb showed reduced virulence with weaker splenic pathological damage and significantly lower splenic bacterial load compared to wild-type a19, indicating accelerated clearance in the host. Δbtpb induced stronger humoral and cellular. 12522 vaccine live attenuated vaccine role