has role protective antigen role protective antigen Yersinia pseudotuberculosis protein pYV0055 Complexes of YopB (pYV0055), YopD, and YopE (BDE) secreted by Yersinia pseudotuberculosis were purified by affinity chromatography and used as immunogens to determine if antibodies to the translocon could provide protection against Y. pestis in mice. The YopB protein or a complex of YopB and YopD (BD) was purified and determined by vaccination to be immunogenic in mice. Mice actively vaccinated with BD or passively vaccinated with anti-BD serum were protected against lethal challenge with F1(-) Y. pestis [PubMed: 18765742]. Allen Xiang Protegen ID: 354; NCBI Gene GI: 2952948; NCBI Protein GI: 51593897; NCBI Protein Accession: YP_068464; NCBITaxon: 273123 Oliver He protein