has role protective antigen role protective antigen Hantavirus protein N protein [Topografov virus] Protegen ID: 491; NCBI Protein GI: 4757106; NCBITaxon: 83192 protein Oliver He To investigate the ability of recombinant N (rN, nucleocapsid proteins) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala (PUUV), Topografov (TOPV), Andes (ANDV), and Dobrava (DOBV) viruses and subsequently challenged them with PUUV. All animals immunized with PUUV and TOPV rN were completely protected [PubMed: 12050380]. Allen Xiang