has role protective antigen role protective antigen Herpes simplex virus type 1 and 2 protein ICP27 from Herpes simplex virus type 2 Particle-mediated DNA vaccination of mice with a DNA plasmid-encoding ICP27 resulted in the induction of ICP27-specific IFN-gamma and TNF-alpha production in Balb/c mice. When the DNA vaccine was supplemented with as little as 50ng of a vector encoding the A and B subunits of the Escherichia coli heat labile enterotoxin (LT), animals were profoundly protected from morbidity and mortality [PubMed: 16621198]. Protegen ID: 503; NCBI Protein GI: 124181; NCBITaxon: 10315 protein Oliver He Allen Xiang