<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/VO?iri=http://purl.obolibrary.org/obo/VO_0011202"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
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     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002162 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
        <rdfs:label>in taxon</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
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    <!-- http://purl.obolibrary.org/obo/OPL_0000332 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000332">
        <rdfs:label>Neospora caninum tachyzoite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000457 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000457">
        <rdfs:label>protective antigen role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001232 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0001232">
        <rdfs:label>protective antigen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010828 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0010828">
        <rdfs:label>Neospora caninum protein</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011202 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0011202">
        <rdfs:label>NcDG1</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
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        </rdfs:subClassOf>
        <rdfs:comment>Separate groups of gerbils were immunized with purified recombinant proteins singly or in combinations and animals were then challenged with N. caninum.  The protective efficacy of each vaccination was determined by assessing animal survival rate.  The highest protection efficacy was observed for combined vaccination with NcSRS2 and NcDG1 (67.5% survival) compared to control (17.4% survival).  Vaccination with NcDG1 alone elicited 62.5% survival in the challenge model [PubMed: 15793355].</rdfs:comment>
        <ns3:IAO_0000117>Allen Xiang</ns3:IAO_0000117>
        <rdfs:seeAlso>Protegen ID: 618; NCBI Protein GI: 2149142; NCBITaxon: 29176</rdfs:seeAlso>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
    </Class>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



