<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/VO?iri=http://purl.obolibrary.org/obo/VO_0011212"?>
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     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
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     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002162 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
        <rdfs:label>in taxon</rdfs:label>
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
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    <!-- http://purl.obolibrary.org/obo/OPL_0000386 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000386">
        <rdfs:label>Plasmodium yoelii merozoite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000457 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000457">
        <rdfs:label>protective antigen role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001232 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0001232">
        <rdfs:label>protective antigen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011212 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0011212">
        <rdfs:label>MSP1 from P. yoelii str. 17XNL</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000386"/>
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            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns3:IAO_0000117>Allen Xiang</ns3:IAO_0000117>
        <rdfs:seeAlso>Protegen ID: 628; NCBI Gene GI: 3791597; NCBI Protein GI: 82596427; NCBI Protein Accession: XP_726257; NCBITaxon: 352914</rdfs:seeAlso>
        <rdfs:comment>Researchers found that the cysteine-rich, carboxyl-terminal region of the MSP-1 protein from the rodent malarial parasite Plasmodium yoelii yoelii can be expressed in a native configuration as a fusion protein in Escherichia coli. This recombinant polypeptide elicits antibodies in mice which recognize the native parasite MSP-1. Most significantly, both inbred and outbred mice immunized with the fusion protein in Ribi adjuvant are partially and in some cases completely protected against challenge infection with an otherwise lethal parasite strain [PubMed: 8363656].</rdfs:comment>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015474 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0015474">
        <rdfs:label>Plasmodium yoelii protein</rdfs:label>
    </Class>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



