<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/VO?iri=http://purl.obolibrary.org/obo/VO_0011229"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002162 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
        <rdfs:label>in taxon</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/OPL_0000242 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000242">
        <rdfs:label>Plasmodium falciparum erythrocytic merozoite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000457 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000457">
        <rdfs:label>protective antigen role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001232 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0001232">
        <rdfs:label>protective antigen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011229 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0011229">
        <rdfs:label>EMP1</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:seeAlso>Protegen ID: 645; NCBI Protein GI: 2961468; NCBITaxon: 5833</rdfs:seeAlso>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <ns3:IAO_0000117>Allen Xiang</ns3:IAO_0000117>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
        <rdfs:comment>Immunized animals were challenged in vivo with various parasite strains or clones of malaria. Immunization with the PfEMP1-DBL1 alpha domain abolished the PfEMP1-dependent sequestration of the homologous strain in immunized rats and substantially inhibited parasite adhesion in immunized monkeys. Protection against sequestration of heterologous parasite strains was also confirmed by direct or indirect challenge in the rat model [PubMed: 17074852].</rdfs:comment>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015471 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0015471">
        <rdfs:label>Plasmodium falciparum protein</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



