<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/VO?iri=http://purl.obolibrary.org/obo/VO_0011241"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002162 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
        <rdfs:label>in taxon</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/OPL_0000242 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000242">
        <rdfs:label>Plasmodium falciparum erythrocytic merozoite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000457 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000457">
        <rdfs:label>protective antigen role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001232 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0001232">
        <rdfs:label>protective antigen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011241 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0011241">
        <rdfs:label>Hsp90</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns3:IAO_0000117>Allen Xiang</ns3:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:seeAlso>Protegen ID: 657; NCBI Protein GI: 1093612; NCBITaxon: 5833</rdfs:seeAlso>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
        <rdfs:comment>A monkey vaccination trial using a Plasmodium falciparum protein fraction containing antigens of 90-110 kDa is reported.   Three monkeys out of five resisted a heavy challenge dose of highly virulent parasites.  Hsp90 was found in the immunoprecipitates obtained with SERP antisera. Interestingly, the response to hsp90 correlated with protection, high antibody titres being found only in the protected monkeys [PubMed: 8303938].</rdfs:comment>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015471 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0015471">
        <rdfs:label>Plasmodium falciparum protein</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



