<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/VO?iri=http://purl.obolibrary.org/obo/VO_0011260"?>
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     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
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     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
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    <!-- http://purl.obolibrary.org/obo/VO_0000457 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000457">
        <rdfs:label>protective antigen role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001232 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0001232">
        <rdfs:label>protective antigen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010835 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0010835">
        <rdfs:label>Leishmania major protein</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011260 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0011260">
        <rdfs:label>LACK</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
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            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
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        </rdfs:subClassOf>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
        <rdfs:seeAlso>Protegen ID: 734; NCBI Nucleotide GI: 1276476; NCBI Protein GI: 1276477; NCBI Protein Accession: AAA97577.1; NCBITaxon: 5664</rdfs:seeAlso>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge.  A truncated portion of the LACK antigen (LACKp24) was able to induce the highest protective effect compared to other constructs.  The DNA vaccine encoding LACK was able to induce partial protection in mice [PubMed: 18951941].</rdfs:comment>
        <ns3:IAO_0000117>Allen Xiang</ns3:IAO_0000117>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



