has role in taxon Trypanosoma cruzi trypomastigote protective antigen role protective antigen Trypanosoma cruzi protein T. cruzi TS protein Allen Xiang To develop a vaccine strategy taking advantage of activated CD8(+)T cells,a DNA vaccine, designated pGFP-TSA1, encoding a fusion protein linking GFP to a single CTL epitope of TSA1(TS), a leading candidate for vaccine against T. cruzi was constructed. C57BL/6 mice vaccinated with this plasmid showed suppressed parasitemia and prolonged survival. Vaccination with pGFP-TSA1 enhanced epitope-specific cytotoxicity and IFN-gamma secretion by CD8(+)T cells [PubMed: 18321749]. Protegen ID: 757; NCBI Protein GI: 258547365; NCBITaxon: 5693 Oliver He