has role protective antigen role protective antigen Leishmania amazonensis protein CP cysteine proteinase Oliver He protein Allen Xiang A 500 bp fragment encoding an isoform of cysteine proteinase (CP) from Leishmania (Leishmania) amazonensis was subcloned and expressed in the pHis vector, resulting in a recombinant protein of 24 kDa, rLacys24. Immunization of BALB/c mice with rLacys24 plus CFA adjuvant resulted in a low but significant decrease of foot lesions after challenge with L. (L.) amazonensis compared to those exhibited by control mice [PubMed: 19735658]. Protegen ID: 758; NCBI Nucleotide GI: 30142041; NCBI Protein GI: 30142042; NCBI Protein Accession: AAN34826.1; NCBITaxon: 5659