<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/VO?iri=http://purl.obolibrary.org/obo/VO_0011305"?>
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     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
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     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

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        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
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    //
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    <!-- http://purl.obolibrary.org/obo/VO_0000457 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000457">
        <rdfs:label>protective antigen role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001232 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0001232">
        <rdfs:label>protective antigen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010841 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0010841">
        <rdfs:label>Western equine encephalomyelitis virus protein</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011305 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0011305">
        <rdfs:label>E2 from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010841"/>
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        <rdfs:comment>This report describes the successful cloning of the E2 gene of WEEV and expression in Escherichia coli as inclusion bodies.  The immunogenicity of the refolded rE2 protein was demonstrated by strong humoral and cell mediated immune (CMI) responses in rE2-immunized BALB/c mice. The current study also demonstrated that rE2-immunized mice could be partially protected from lethal challenge of WEEV [PubMed: 17499379].</rdfs:comment>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <ns3:IAO_0000117>Allen Xiang</ns3:IAO_0000117>
        <rdfs:seeAlso>Protegen ID: 773; NCBI Protein GI: 29611992; NCBITaxon: 11039</rdfs:seeAlso>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
    </Class>
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