dendritic cell physiology trait Langerhans cell physiology trait Any measurable or observable characteristic related to the function of or processes in the stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. VT:0005362 Trait.ontology Langerhans cell function