collagenase-solubilized glomerular basement membrane collagenase-solubilized rat glomerular basement membrane 2014-01-10T15:48:30Z A condition in which the main influencing factor is a relatively undefined mix of macromolecules such as glycoproteins, proteoglycans, and fragmented collagens, derived from the basement membrane of renal glomeruli from rats (i.e., members of the species Rattus norvegicus) via treatment with collagenase, an enzyme that catalyzes the hydrolysis of peptide bonds in triple helical regions of collagen, one of the major components of basement membranes. A basement membrane is an organised multi-molecular extracellular matrix which is characteristically found under epithelial and endothelial cells. XCO:0000387 collagenase-solubilized rat GBM experimental_condition_ontology jsmith