steroid hormone aldosterone 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al 2018-12-27T15:39:58Z A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. MESH:D000450 PMID:8770880 XCO:0000599 experimental_condition_ontology sjwang